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Cells exposed to TB-500 appeared to express increased levels of angiopoietin-2, the Tie2 receptor, and vascular endothelial growth factor A (VEGFA)

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Among other variables, three studies [24, 26, 27] have recorded patient views on the administration route, and record a high level of acceptance of the oral route, the advantages of which include avoiding the displacement of patients to receive injections, avoiding the discomfort of injection, and a reduction in treatment costs [28, 29]