Maes, T
Mechanistic studies have established that Dihexas procognitive and synaptogenic effects are mediated by the hepatocyte growth factor (HGF) / c-Met receptor system rather than by the classical AT 4 receptor, despite Dihexas structural origin as an angiotensin IV derivative
According to the 2022 review, other supplements that might work include: Pantogar Capsaicin Omegas 3 and 6 with antioxidants Zinc Pumpkin seed oil But keep in mind that nutritional supplements are often only helpful if theres a deficiency at play, says Hallajian

Ingredients: Water, Dibutyl Adipate, Butyloctyl Salicylate, Ethylhexyl Triazone, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Propanediol, Niacinamide, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Terephthalylidene Dicamphor Sulfonic Acid, 1,2-Hexanediol, Polyglyceryl-3 Distearate, Ethylhexyl Methoxycrylene, Glycerin, VP/Hexadecene Copolymer, Panthenol, Poly C10-30 Alkyl Acrylate, Sodium Polyacryloyldimethyl Taurate, Tromethamine, Ammonium Polyacryloyldimethyl Taurate, Glutathione (500ppm), Betaine, Hydroxypropyl Methylcellulose Stearoxy Ether, Fragrance, Glyceryl Stearate Citrate, Ethylhexylglycerin, Adenosine, t-Butyl Alcohol, Hydrolyzed Hyaluronic Acid, Maltodextrin, Persea Gratissima (Avocado) Fruit Extract, Thioctic Acid, Brassica Campestris (Rapeseed) Sterols,Cholesterol, PEG-5 Rapeseed Sterol, Ceteth-3, Ceteth-5, Hydrogenated Lecithin, Sodium Ascorbyl Phosphate, Potassium Cetyl Phosphate, Disodium EDTA
PubMed , HSS Journal , July 2025, p