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429,430,431 Sustained high levels of insulin demand will eventually give rise to functionally compromised or physical loss of -cells, which culminate in hyperglycemia and diabetes

Meng Y, Wang K, Wang T, Tu Y, Gong S, Zhang Y, Zhang G, Au W, Christiani DC, Xia Z-L (2021) Early occupational exposure to lead on neutrophil-to-lymphocyte ratio and genotoxicity

Sci Transl Med 5:185ra162 Kerr JB, Hutt KJ, Cook M, Speed TP, Strasser A, Findlay JK, Scott CL (2012) Cisplatin-induced primordial follicle oocyte killing and loss of fertility are not prevented by imatinib