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Tirzepatide mimics the action of two natural hormones released by intestinal cells: glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)

Small doses of triiodothyronine can change some risk factors associated with abdominal obesity

For example, someone with a BMI of 33 might be estimated to lose 30 pounds or 15% of their body weight in six to 12 months

Zhang C et al (2023) Post-ovulatory aging affects mitochondria, spindle and protein metabolism in mouse oocytes

Some hold the view that low and medium doses of GLP-1RAs may have muscle-protective potential, while high doses are more often accompanied by a decrease in muscle mass