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Funding Publication costs for this article were funded by the authors' institutions

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Folate supplementation without adequate B12 can also partially mask B12-related anaemia in routine blood tests, making deficiency harder to detect through a standard CBC alone (Cikot et al., 2001, British Journal of Nutrition)

You may also report suspected adverse reactions directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk

Ethical approval was not required for this systematic review, as it uses publicly available, de-identified data from ClinicalTrials.gov without direct patient interaction