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Nanoparticles composed of various nanomaterials have been shown to regulate anti-tumor immunity by reducing circulating and tumor-infiltrating MDSCs, altering MDSC phenotypes, or inhibiting MDSCs functions, such as nanocapsules, metal-organic frameworks (MOFs)-based nanoparticles, polymeric micelles, polymers, dendritic macromolecules, liposomes, etc ( Figure 4 ), and we will introduce the nanoparticles that affect MDSCs in detail in the following content

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