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Antioxidants came to public attention in the 1990s, when scientists began to understand that free radical damage was involved in the early stages of artery-clogging atherosclerosis
346 ROS immediately trigger endothelial cells to produce the matricellular protein thrombospondin-1 (TSP-1), which contributes to the conversion of TGF-1 into its active form following PHx
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Activating the alpha-7 nicotinic acetylcholine receptor (7nAChR) may provide antioxidant effects by lowering oxidative stress in endothelial cells
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