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While the researchers in this study utilized pre-existing data available to them and did not directly measure alcohol or opioid use, they found clinically meaningful associations between semaglutide/tirzepatide-type weight loss medication prescription and reductions in alcohol intoxication and opioid poisoning events in patients at risk for these deleterious health outcomes

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A 2023 systematic review (Sodhi et al., Clinical Gastroenterology and Hepatology) examined endoscopy findings in GLP-1 agonist users with reflux symptoms

This does not mean compounded medications are categorically unavailable

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