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For example, UFC suspended Chad Mendes in 2016 for using GHRP-6, a growth hormone-releasing peptide

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strong depolarization of the post-synaptic cell completely displaces the magnesium ions that block NMDA ion channels and allows calcium ions to enter a cell probably causing LTP, while weaker depolarization only partially displaces the Mg 2+ ions, resulting in less Ca 2+ entering the post-synaptic neuron and lower intracellular Ca 2+ concentrations (which activate protein phosphatases and induce long-term depression, LTD)

Again this all depends on your Maximal Recoverable Volume (MRV) the amount you can do and still recover from week on week

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