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Renal effects, including acute kidney injury, have been reported rarely in post-marketing surveillance, typically in the context of severe gastrointestinal adverse effects leading to dehydration

You have already completed the starting dose and are progressing into more effective territory

Prioritize protein (0.7 to 1.0 grams per pound of target body weight), eat frequent small meals rather than large infrequent ones, limit high-fat foods during dose increases to reduce nausea, stay hydrated, and avoid alcohol (which worsens both GI side effects and calorie intake)

Beyond-use dates may vary depending on the specific formulation

If you suspect an overdose, seek immediate medical attention