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doi:10.3389/fcvm.2018.00001 Santilli F, Dav G, Patrono C

Most users report visible improvements starting around 8 to 12 weeks of consistent injectable use, with optimal results building over 12 or more weeks of continuous administration

By the time many adults reach their 40s, natural levels may start to drop significantly

FIGURE 13 In the aforementioned study by Hsieh and collaborators (Hsieh et al., 2017) that focused on the ischemic muscle model (achieved via removal of the femoral artery), the pro-angiogenic effects of BPC 157 are evident, given the increased expression, internalization of vascular endothelial growth factor receptor 2 (VEGFR2), and the activation of the VEGFR2-Akt-eNOS signaling pathway (Hsieh et al., 2017)

Other studies: Includes retinal degeneration, neuroprotection, and oxidative stress indicators