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Good health decisions are rarely made in a vacuum

This includes a number of politicians who have largely ignored the air pollution problems About 253,000 early deaths were blamed on fine, inhalable particles known as PM2.5 in levels that surpassed the World Health Organizations (WHO) maximum limits

Additional promising targets include TGF--driven fibrogenic signaling and oxidative stress pathways propagated by advanced glycation end-products and their receptor RAGE (Zhou et al., 2025b), IL-6 neutralization (ziltivekimab), and anti-fibrotic candidates like pirfenidone or ASK1 inhibition (selonsertib) (Figure 6)

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In blood pressure studies, NaBPC157 (without effect on basal normal values) compared with L-arginine has both a mimicking effect (impaired L-NAME-blood pressure increase, applied prophylactically and decreased already raised L-NAME values, given at the time of the maximal L-NAME-blood pressure increase (i.e., 10 minutes after L-NAME)) and a preventative activity (L-arginine-induced moderate blood pressure decrease was prevented by NaBPC157 pre-treatment)