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188 YamadaY.KatagiriH.HamamotoY.DeenadayalanS.NavarriaA.NishijimaK.et al (2020)

Heres a chart, based on data from this study: People with obesity or metabolic syndrome have chronically high GLP-1 levels, possibly because the diet that tends to cause obesity and metabolic syndrome is high in sugar and simple carbs, which raise blood sugar and demand a lot of GLP-1

In IBS rats, exendin-4 reduced stress-induced defecation and pain sensitivity through gut neurons [108]

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