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Advise patients to take precautions to avoid fluid depletion

Use electrolyte replacement such as ORS to meet electrolyte requirements

Staying well-hydrated is essential, particularly if experiencing vomiting or diarrhoea, as dehydration can lead to acute kidney injury in severe cases

While some clinicians have observed that patients with a pre-existing history of migraine or tension-type headaches might be more susceptible to experiencing headaches when initiating semaglutide therapy, this association has not been systematically studied in large-scale trials

This extended half-life is also why results take time to appear