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GLP-1 receptor activation also increases intracellular calcium concentrations, particularly in pancreatic -cells, which is crucial for insulin secretion (Chothave et al., 2024)

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GOLD was used to dock T1 , T2 , T3 and T5 into the active site of the X-ray (PDB ID: 2Y9X) and a human tyrosinase model (built by Multiple sequences alignment and Homology modeling of Discovery Studio v.4.0 using the structure of mushroom tyrosinase as a template (PDB ID: 2Y9X) (Supplementary Fig