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10.2 Lack of direct comparison with emerging therapies Most comparative trials compared tirzepatide against semaglutide at a dose of 1 mg, and head-to-head evaluations with higher doses of semaglutide 2.4 mg (approved for obesity), or with other oral GLP-1 agents are currently lacking

about 100 million people affected Sign on facade of CapitalOne cafe, a combined cafe and banking center, is pictured in downtown Walnut Creek, California on November 17, 2017

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