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Retinaldehyde is then oxidized to generate retinoic acid in the presence of the aldehyde dehydrogenase 1 (ALDH1) family enzyme, which is then converted into the product 4-oxo retinoic acid

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Ceramide NP and Centella Asiatica Extract also help support the skin barrier and maintain moisture balance

Nausea, headaches, drowsiness and a mild tingling sensation are also other less serious side effects which have been associated with the use of this medication

Ice : Applying ice packs to the affected area for 15-20 minutes at a time, several times a day, can help reduce pain and inflammation