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These changes were observed at the site of active disease, namely the ileum in Tnf ARE mice ( Figure 1B ) and the colon in IL-10 -/- mice, Rag2 -/- mice adoptively transferred with colitogenic CD4 + CD25 - T cells, and C57BL/6 mice infected with C

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Encouraging a culture of reporting among both patients and clinicians is essential to ensuring that medicines, including novel agents such as retatrutide, are used as safely as possible

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While North America held the largest market share for GLP-1 RA medications in 2024, with Europe following, Asia-Pacific is expected to exhibit the fastest growth market due to rising diabetes and obesity rates 13