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10.1016/j.mito.2013.01.008 Mitochondrion 183 VenkatakrishnanP.NakayasuE

The glutathione peptide of one inhibitor, termed productive binding, occupies the G-subsite with multiple interactions similar to those observed for other glutathione S-transferases, while the glutathione backbone of the second inhibitor, termed unproductive binding, exhibits only weak interactions mediated by two polar contacts

inhibitor landscape)

The objective is not rapid acceleration, but improved metabolic consistency under structured care