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Comai S, Bertazzo A, Brughera M, Crotti S

Some companies will recommend a loading phase of 20g per day for 1 week, though the research is unclear whether this is really needed

[7] GLP-1 plays a huge part in metabolic health [8,9,10,11] Slowing digestion Promoting feelings of fullness (satiety) Reducing appetite Signaling insulin release Controlling blood sugar levels Preventing formation of new fat cells Stimulating fat burning (called thermogenesis) Maintaining desired body weight Bitters activate and increase GLP-1 to help deliver all of these metabolic benefits

Again, people switch for many reasons: fewer side effects, a dosing schedule that feels easier, or insurance that covers one option but not another

Murphy et al., 2022)