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Currently, it has been established that several probiotics, such as VSL#3, are beneficial in the treatment of UC and can alleviate the symptoms of UC by reducing the inflammatory response and immune response
Extracellular vesicles EVs represent a diverse population of small, non-replicating, membrane-encapsulated particles released by nearly all cell types.113 114 Based on their biogenesis and size, EVs are categorised into three main groups: exosomes (50150 nm), microvesicles (1001000 nm) and apoptotic bodies (5002000 nm).113 114 These nanosized particles carry a distinct molecular signature composed of proteins, RNA (including miRNAs and long non-coding RNAs), lipids and even DNA fragments, which reflect the cell type of origin and the specific homeostatic or pathological stimuli that trigger their release.115 EVs are emerging as sophisticated mediators of intercellular communication
