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Administration of PLX3397 to mice For pharmacological ablation of microglia, PLX3397 was administrated to mice by supplementation (290 mg/kg of PLX3397 (#C-1271

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2007 in the New England Journal of Medicine (NCT00123253, n = 412 HIV-infected adults, 2:1 tesamorelin to placebo, 26-week primary phase) met its pre-specified visceral-adipose-tissue primary endpoint by CT versus placebo, with concurrent IGF-1 elevation from baseline [6]