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Other mechanisms that regulate the intracellular iron abundance, such as the exportation of iron via various multivesicular bodies and exosomes carrying ferroportin or prominin2-mediated ferritin, can also affect the cellular sensitivity to ferroptosis, as they deplete the cellular iron and accelerate the lipid peroxidation (53) ( Figure 1 )

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For example, shifts in estrogen during perimenopause and menopause can affect sleep, recovery, weight, skin, and muscle tone

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Most people strive to maintain a healthy lifestyle by eating well, staying active, and taking care of their bodies