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Beta-3 adrenergic receptors, the primary target of AOD-9604, are highly expressed in white and brown adipose tissue but have minimal presence in appetite-regulating brain regions

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In our investigations, we observed that robust angiogenesis, characterized by grossly visible neovascularization and a marked increase in CD31-positive luminal structures by immunohistochemistry, was a prominent histological feature of healing in animal models of tissue injury treated with BPC157