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It is sensible to initiate therapy with a partial dose, since in some instances the thyroid gland may be nonsuppressible even though functioning at a level below normal
While some evidence for this effect is for acute high-dose exposure (Yadla 2013
This is largely due to the rise and accessibility of GLP-1 receptor agonist drugs like Ozempic and Wegovy
Timeline: when patients notice changes The first changes most patients report are sleep-related, typically improved sleep depth and morning energy levels, appearing within weeks two to three of the first cycle
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